Centre for Cancer Research

Innate immunity publications

2008
Gantier MP, Tong S, Behlke MA, Xu D, Phipps S, Foster PS and Williams BRG (2008) TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages. J Immunol 180(4):2117-2124.

2007
Gantier MP, Baugh JA and Donnelly SC (2007) Nuclear transcription of long hairpin RNA triggers innate immune responses. J Interferon Cytokine Res 27(9):789-797.

Gantier MP, Sadler AJ and Williams BRG (2007) Fine-tuning of the innate immune response by microRNAs. Immunol Cell Biol 85(6):458-462.

White CL, Whitmore MM and Williams BRG (2007) Enlarged spleens without enlarged lymph nodes in tlr3^-/- pkr^-/- mice. J Interferon Cytokine Res 27(1):6-12.

Whitmore MM, Iparraguirre A, Kubelka L, Weninger W, Hai T and Williams BRG (2007) Negative regulation of TLR-signaling pathways by activating transcription factor-3. J Immunol 179(6):3622-3630.

2005
Elco CP, Guenther JM, Williams BR and Sen GC (2005) Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-κB, and interferon but not toll-like receptor 3. J Virol 79:3920-3929.

Malathi K, Paranjape JM, Bulanova E, Shim M, Guenther-Johnson JM, Faber PW, Eling TE, Williams BRG and Silverman RH (2005) A transcriptional signaling pathway in the IFN system mediated by 2’-5’-oligoadenylate activation of RNase L. Proc Natl Acad Sci USA 102:14533-14538.

2004
Chang H-M, Paulson M, Holko M, Rice CM, Williams BRG, Marié I and Levy DE (2004) Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity. Proc Natl Acad Sci USA 101:9578-9583.

Dong B, Zhou Q, Zhao J, Zhou A, Harty RN, Bose S, Banerjee A, Slee R, Guenther J, Williams BRG, Wiedmer T, Sims PJ and Silverman RH (2004) Phospholipid scramblase 1 potentiates the antiviral activity of interferon. J Virol 78:8983-8993.

Whitmore MM, DeVeer MJ, Edling A, Oates RK, Simons B, Lindner D and Williams BRG (2004) Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res 64:5850-5860.

2003
Leitner WW, Hwang LN, de Veer MJ, Zhou A, Silverman RH, Williams BRG, Dubensky TW, Ying H and Restifo NP (2003) Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Nat Med 9:33-39.

Williams BRG and Sen GC (2003) A viral on/off switch for interferon. Science 300:1100-1101.