Centre for Cancer Research

RNA interference publications

2008
Zamanian-Daryoush M, Marques JT, Gantier MP, Behlke MA, John M, Rayman P, Finke J and Williams BRG (2008) Determinants of cytokine induction by small interfering RNA in human peripheral blood mononuclear cells. J Interferon Cytokine Res 28(4):221-233.

2007

Bernkopf DB and Williams ED (2008) Potential role of EPB41L3 (Protein 4.1B/Dal-1) as a target for treatment of advanced prostate cancer. Expert Opin Ther Targets 12(7):845-853.

O'Brien PM, Davies MJ, Scurry JP, Smith AN, Barton CA, Henderson MJ, Saunders DN, Gloss BS, Patterson KI, Clancy JL, Heinzelmann-Schwarz VA, Murali R, Scolyer RA, Zeng Y, Williams ED, Scurr L, DeFazio A, Quinn DI, Watts CKW, Hacker NF, Henshall SM and Sutherland RL (2008) The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro. Br J Cancer 98:1085-1093.

Thompson EW and Williams ED (2008) EMT and MET in carcinoma-clinical observations, regulatory pathways and new models. Clin Exp Metastasis; advance online publication 20 June 2008 (doi:10.1007/s10585-008-9189-8).

2006
Marques JT, Devosse T, Wang D, Zamanian-Daryoush M, Serbinowski P, Hartmann R, Fujita F, Behlke MA and Williams BRG (2006) A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. Nat Biotechnol 24:559-565.

Nguyen QN, Chavli RV, Marques JT, Conrad II PG, Wang D, He W, Belisle BE, Zhang A, Pastor LM, Witney FR, Morris M, Heitz F, Divita G, Williams BRG and McMaster GK (2006) Light controllable siRNAs regulate gene suppression and phenotypes in cells. Biochim Biophys Acta 1758:394-403.

2005
de Veer MJ, Sledz CA and Williams BRG  (2005) Detection of foreign RNA: implications for RNAi. Immunol Cell Biol 83:224-228.

Marques JT and Williams BRG (2005) Activation of the mammalian immune system by siRNAs. Nat Biotechnol 23:1399-1405.

Sledz CA and Williams BRG (2005) RNA interference in biology and disease. Blood 106:787-794.

2003
Sledz CA, Holko M, de Veer MJ, Silverman RH and Williams BRG (2003) Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 5:834-839.

Sledz CA and Williams BRG (2003) RNA interference and interferon. Discovery Med 3:30-31.