Centre for Cancer Research

MIMR's newest research centre, the Centre for Cancer Research, was established in January 2006. Led by Institute Director, Professor Bryan Williams, scientists working in the Centre for Cancer Research are dedicated to studying the impact of cancer incidence, in an effort  to learn more about the growth and development of different cancers and to discover new cancer therapies.

The Cancer Research team carries out its own research, but also collaborates closely with scientists from MIMR’s other centres and the Monash Health Research Precinct to share expertise, resources and knowledge into a range of cancers, including breast, endometrial, ovarian, stomach and prostate cancers as well as leukaemia. CCR scientists are particularly interested in the link between inflammatory processes and cancer as well as the role of cancer stem cells.

Recent publications:

Zeng Y, Opeskin K, Goad J and Williams ED (2006) Tumor-induced activation of lymphatic endothelial cells via vascular endothelial growth factor receptor-2 is critical for prostate cancer lymphatic metastasis. Cancer Res. 66:9566-75.

Chaffer CL, Thomas DM, Thompson EW and Williams ED (2006) PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma. BMC Cancer 6:53-64.

Gabel F, Wang D, Madern D, Sadler A, Dayie K, Zamanian Daryoush M, Schwahn D, Zaccai G, Lee X and Williams BRG (2006) Dynamic flexibility of double-stranded RNA activated PKR in solution. J Mol Biol 359:610-623.

Holko M and Williams BRG (2006) Functional annotation of IFN-α-stimulated gene expression profiles from sensitive and resistant renal cell carcinoma cell lines. J Interferon Cytokine Res 26:534-547. Supplementary figure