Centre for Cancer Research

RNA interference publications

2010
Gantier MP (2010) New perspectives in microRNA regulation of innate immunity. J Interferon Cytokine Res 30:283-289.

Gantier MP, Tong S, Behlke MA, Irving AT, Lappas M, Nilsson UW, Latz E, McMillan NAJ, Williams BRG (2010) Rational design of immunostimulatory siRNAs. Mol Ther 18:785-795.

Gantier MP, Williams BRG (2010) Monitoring innate immune recruitment by siRNAs in mammalian cells. Methods Mol Biol 623:21-33.

McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O’Neill LAJ (2010) IL-10 inhibits miR-155 induction by Toll-like receptors. J Biol Chem 285:20492-20498.

2009
Gantier MP, Williams BRG (2009) siRNA delivery not Toll-free. Nat Biotechnol 27:911-912.

2008
Armstrong ME, Gantier M, Li L, Chung WY, McCann A, Baugh JA, Donnelly SC (2008) Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism. J Immunol 180:7125-7133.

Zamanian-Daryoush M, Marques JT, Gantier MP, Behlke MA, John M, Rayman P, Finke J and Williams BRG (2008) Determinants of cytokine induction by small interfering RNA in human peripheral blood mononuclear cells . J Interferon Cytokine Res 28(4):221-233.

2007
Gantier MP and Williams BRG (2007) The response of mammalian cells to double-stranded RNA. Cytokine Growth Factor Rev 18:363-371.

2006
Marques JT, Devosse T, Wang D, Zamanian-Daryoush M, Serbinowski P, Hartmann R, Fujita F, Behlke MA and Williams BRG (2006) A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. Nat Biotechnol 24:559-565.

Nguyen QN, Chavli RV, Marques JT, Conrad II PG, Wang D, He W, Belisle BE, Zhang A, Pastor LM, Witney FR, Morris M, Heitz F, Divita G, Williams BRG and McMaster GK (2006) Light controllable siRNAs regulate gene suppression and phenotypes in cells. Biochim Biophys Acta 1758:394-403.

2005
de Veer MJ, Sledz CA and Williams BRG  (2005) Detection of foreign RNA: implications for RNAi. Immunol Cell Biol 83:224-228.

Marques JT and Williams BRG (2005) Activation of the mammalian immune system by siRNAs. Nat Biotechnol 23:1399-1405.

Sledz CA and Williams BRG (2005) RNA interference in biology and disease. Blood 106:787-794.

2003
Sledz CA, Holko M, de Veer MJ, Silverman RH and Williams BRG (2003) Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 5:834-839.

Sledz CA and Williams BRG (2003) RNA interference and interferon. Discovery Med 3:30-31.