Centre for Urological Research Projects

Role of the inhibin alpha subunit in advanced prostate cancer

One of the most intractable aspects of prostate cancer treatment and therapy is determining which patients will develop life-threatening metastatic cancer and thus require therapeutic intervention from those patients with relatively latent disease who would benefit from a non-intervention approach. There is, therefore, an urgent need for new markers to distinguish between these two groups. We propose the hypothesis that inhibin alpha subunit, a tumor suppressor gene, is tumor promoting and pro-metastatic in advanced prostate cancer. Studies under this project will seek to establish a relationship between elevated inhibin alpha subunit expression levels and metastasis in both animal models and in human prostate tissues.

Supervisor: Dr Preetika Balanathan
Telephone: +61 3 9594 7323